All Children's Hospital Logo

Health Information Library

Parents > Q&A > Medical Conditions > Can a Child Have Fifth Disease More Than Once?
Can a Child Have Fifth Disease More Than Once?

Do kids have a natural immunity to fifth disease once they've had the virus?
- Rikki

Usually, kids who've been infected with the virus that causes fifth disease (parvovirus B19) become immune to it and won't become infected again.

Fifth disease is one of the most common and contagious childhood illnesses. Fortunately, fifth disease usually doesn't make a child very ill. A "slapped-cheek" rash on the face that spreads to the body following mild, cold-like symptoms (like a fever and runny nose) usually are the only symptoms. But fifth disease can be dangerous to pregnant women and people with certain medical conditions.

The best way to avoid infections like fifth disease is to encourage frequent hand washing.

Reviewed by: Larissa Hirsch, MD
Date reviewed: April 2015

Related Articles
P    Erythema Multiforme
P    Fifth Disease
P    Hand, Foot, and Mouth Disease
P    Hives (Urticaria)
P    Roseola
P    Rubella (German Measles)
P    Scarlet Fever
P    What Are Germs?
P    Why Is Hand Washing So Important?
Note: All information is for educational purposes only. For specific medical advice, diagnoses, and treatment, consult your doctor.
© 1995-2015 KidsHealth® All rights reserved. Images provided by iStock, Getty Images, Corbis, Veer, Science Photo Library, Science Source Images, Shutterstock, and

Additional Info

Pocket Doc Mobile App
Maps and Locations (Mobile)
Programs & Services
For Health Professionals
For Patients & Families
Contact Us
Find a Doctor

All Children's Hospital
501 6th Ave South
St. Petersburg, FL 33701
(727) 898-7451
(800) 456-4543

Use Normal Template
© 2015 All Children's Hospital - All Rights Reserved