Cancer Research

About Us

The Pediatric Hematology/Oncology Program at All Children’s Hospital is a major referral center for the West Coast of Florida.  For more than 25 years, All Children’s Hospital has cared for infants, children, and adolescents with cancer and blood diseases.

Pediatric Cancer Care

Since the mid-1980’s, the Pediatric Oncology Program at All Children’s Hospital has been participating in clinical research studies for children with cancer.  These clinical research studies are conducted by the Children’s Oncology Group (COG). The COG is a cooperative group of more than 230 institutions that allows physicians and researchers to track patient’s progress through standardized treatment protocols, then share the data among themselves. Because the data from many patients are combined, clinical trials obtain results more rapidly and new treatments are developed hundreds of times faster. Since childhood cancer is so rare, this is particularly important. By treating children in clinical trials, COG members have increased the cancer cure rate for children from less than 10 percent in the 1950s to nearly 80 percent at present. 

At All Children’s Hospital, 75% of our eligible patients and families participate in research for childhood cancer. Not only are there treatment protocols available that will potentially benefit the individual patient, but there are studies that evaluate the long-term survival issues and parent care-giving needs and look for new ways to improve in these areas as well. 

For more information about the Children’s Oncology Group, please visit their public website, CureSearch.

Stem Cell Transplant

The Blood & Marrow Transplantation program at All Children's is able to evaluate and treat a wide range of childhood illnesses including cancer, blood diseases, immunodeficiencies, inborn errors of metabolism, and bone marrow failure syndromes. Established in 1986, the program currently performs more than twenty hematopoietic stem cell transplants per year. Our four-bed transplant unit is adjacent to the hematology/oncology inpatient wing enhancing collaboration, optimizing staff expertise and assuring continuity of care.

We perform allogeneic and autologous hematopoietic stem cell transplants using bone marrow, peripheral blood, and umbilical cord blood as the cell sources.  We are an approved transplant center that is part of the National Marrow Donor Program.  In addition, we access the New York Placental Blood Center and other registries for potential unrelated donor sources. The Bone Marrow Transplant Center Program has an on-campus laboratory where we perform HLA typing for recipients and donors. Our center is the pediatric affiliate of the H. Lee Moffitt Cancer and Research Center's Blood and Marrow Transplant Program.  We work collaboratively with our colleagues at Moffitt and have a joint program.  All of our cell products are stored, tested and manipulated (if needed) at Moffit.

The Blood & Marrow Transplant Program is an approved transplant center of the Children's Oncology Group (COG). In addition, we are members of the Pediatric Blood & Marrow Transplant Consortium (PBMTC) and participate in this organizations research studies.  The PBMTC is the leading organization focused on bone marrow transplant in the pediatric population, with membership from over 70 bone marrow transplant centers in the USA, Canada, and Australia. The primary focus of the PBMTC is to enhance the safety, availability, and efficacy of pediatric bone marrow transplant.
 
In addition to research protocols done in collaboration with the COG and the PBMTC, exciting laboratory-based studies are being done at All Children's Hospital by members of our transplant team. These studies are supported by extramural funding and are evaluating immunoreconstitution post transplant and graft versus host disease.

Accomplishments

In 2004, the American Society of Clinical Oncology recognized the pediatric cancer program at All Children’s Hospital as one of ten recipients nationwide for its Clinical Trials Participation Award. All Children’s was the only pediatric program in the nation to receive the award, honoring programs for the role they play in furthering the search for cancer cures through participation in clinical research trials.

Affiliations

All Children’s Hospital Cancer program is affiliated with Tampa’s H. Lee Moffitt Cancer Center and Research Institute, an NCI Comprehensive Cancer Center.  This partnership allows us to combine our efforts on research and treatment options and work toward a better understanding of cancer and ultimately a cure.